Owen A. O’Connor, MD, PhD
Chief Scientific Officer
Owen A. O’Connor, MD, Ph.D., an international authority in lymphoma and drug development, with more than 25 years of experience in academic medicine, joined TG as Chief Scientific Officer in May 2020. Dr. O’Connor is widely recognized for his contributions to the field, having pioneered the development of several first-in-class drugs leading to regulatory approval, including the proteasome inhibitor bortezomib, the histone deacetylase (HDAC) inhibitors belinostat and vorinostat, and co-invented and led the international development of pralatrexate, which became the first drug approved for patients with relapsed or refractory peripheral T-cell lymphoma, now approved in over 35 countries around the world. A past member of the Food and Drug Administration’s Oncology Drug Advisory Committee (ODAC), he has also successfully aided in filing New Drug Applications in China, Japan, and Taiwan, as well as the European Medicines Agency (EMA). He has held a number of prestigious leadership positions in the major cancer centers in New York City including Memorial Sloan Kettering Cancer Center, where he held a faculty position for a decade leading the Laboratory of Experimental Therapeutics for the Lymphoid Malignancies, and Chief of the Division of Hematology and Oncology, and Deputy Cancer Center Director at the New York University Medical Center prior to joining Columbia. Dr. O’Connor has published over 200 articles in peer-reviewed journals, books and book chapters and reviews on the management of lymphoma, in addition to being a member of several important advisory boards, including the Scientific Advisory Board for the Lymphoma Research Foundation. He has received countless awards for his research, including being named to America's Top Cancer Doctors, being named among the Top 50 Irish-Americans in Science and Medicine by the Irish government, and being inducted into the New Jersey Inventors Hall of Fame. He is also a recipient of the American Cancer Society Research Professorship, the most prestigious honor bestowed by the Society.