THERAPEUTIC FOCUS
We are focused on diseases known to be caused by the abnormal behavior of B-cells, with a particular focus in autoimmune disorders like multiple sclerosis (MS).
WHAT ARE B-CELLS?
B-cells belong to a family of white blood cells called lymphocytes. Lymphocytes include B-cells, T cells, and NK cells. B-cells play a crucial role in the immune system by producing antibodies to fight infections. By far, diseases attributed to the abnormal growth or function of B-cells are among some of the most common.
WHAT ARE B-CELL DISEASES?
B-cells play an important role in regulating the immune response in both physiological and pathological conditions. B-cell diseases include any disease where the dysregulation of B-cell function or the abnormal growth or behavior of B-cells, leads to disease.
One of the major groups of diseases caused by abnormally functioning B-cells is autoimmune disorders. These diseases result from inappropriate production of antibodies from the B-cells. These antibodies cannot discriminate “self” from “non-self,” and inadvertently mount a disabling immune response against normal organs. An example of a common and very debilitating autoimmune disorder is multiple sclerosis (MS).
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